Stanford stem cell researcher who discovered how to regrow cartilage, dies at 48

Charles “Chuck” Kwok Fai Chan, Ph.D, an assistant professor of surgery at Stanford Medicine and well-known stem cell researcher, died on March 12 at Stanford Hospital. He was 48.

Chan was widely recognized for his pioneering work in identifying stem cells that contribute to bone and cartilage formation, which has foundational implications for treating conditions like osteoarthritis.

“Chuck accomplished a great deal in the short time he had,” said Lloyd Minor, MD, dean of the Stanford School of Medicine and vice president for medical affairs at Stanford University in a statement. “He knew he was working against the clock, which drove him to persevere in his research. He leaves behind a wealth of foundational stem cell discoveries that will inform the future of rejuvenative medicine.”

He added, “Stanford Medicine mourns the loss of such a talented researcher at such an early age.”

Chan was a member of the Stanford Institute for Stem Cell Biology and Regenerative Medicine, member. His discoveries, including isolating mouse and human stem cells vital for bone and cartilage development, are crucial for advancing new healing technologies, according to a Stanford Medicine news release. His work aimed to understand these cells and apply this knowledge to develop treatments for skeletal injuries and degenerative diseases, the release said.

Renowned for his intellectual rigor and innovative spirit, Chan made substantial contributions to the scientific community. He trained numerous young scientists and was always eager to share his knowledge and research findings. His approach to science was characterized by a deep commitment to exploring new frontiers and pushing the boundaries of understanding in regenerative medicine.

Despite his ongoing battle with non-Hodgkin’s lymphoma, Chan remained committed to his work, continuing to mentor young scientists and advance medical science, according to the release.

Chan, a Redwood City resident, died surrounded by his wife, parents, siblings, and some of his closest friends and colleagues. He is survived by his wife, Wan-Jin Lu, of Redwood City, California; parents, Albert and Anna Chan; and his five siblings: Edward Chan, Andrew Chan, Marvin Chan, Brian Chan and Karen Haas. He has nine nephews and nieces.