Town Square

AIDS research in crisis as 'miracle' vaccines actually INCREASE chance of catching virus

Original post made by sue, Professorville, on Mar 22, 2008

The search for a cure for Aids was in crisis last night after it was revealed that two supposed "miracle" vaccines not only fail to protect people from the virus, but could put them at greater risk of becoming infected.

It is a massive blow to Aids research, which has ground to a halt - with seven other trials of similarly designed would-be vaccines either suspended or called off indefinitely.

The US government alone pumps £250million a year into research to try to find a "Holy Grail" vaccine which would put an end to Aids.

Now scientists fear the disastrous outcome of the two most promising trials leaves them back at square one.
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Posted by sue
a resident of Palo Alto High School
on Mar 22, 2008 at 3:47 pm

May be a more key topic for would be messiah obama to address is the

FACT that after we have spent billions of dollars to help them

The rate of HIV/AIDS among the gay and bisexual US black community is

now at 50 PERCENT

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Posted by perspective
a resident of Midtown
on Mar 23, 2008 at 6:16 am

First and most obvious question: Is this like pregnancy rates amongst unmarried women going UP after the pill was introduced? In other words, if you believe you are protected, as those who had the vaccine probably believed, aren't you more likely to engage in risky behavior?

If the rate of infection ( pregnancy ) is, let's say, 1/100 sexual encounters without the vaccine/pill, and 1/1000 with the vaccine/pill, but the number of people engaging in risky behavior goes up 10 fold because they believe they are "protected", then the vaccine/pill will not lower the sheer number of pregnancies/HIV.

I won't be shocked if that is the conclusion of why this "went wrong".

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Posted by joel
a resident of Stanford
on Mar 23, 2008 at 11:59 am

These studies where double blind gold standard research.Those who got the vaccine did not know it was active, those who got the placebo did not know it was inactive

So the analogy with birth control above is false

actually the results of these studies are very bad news indeed for iv drug users and gays in the US.

And devastating for those at risk in Africa and Asia

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Posted by however...
a resident of Midtown
on Mar 23, 2008 at 8:29 pm

if they knew they were part of the study, that in itself could radically affect behavior, as has been noted in other studies.

so, i still will wait until there is more information.

regardless of the cause, the result is still horrible news.

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Posted by Dr. Doctor
a resident of Stanford
on Mar 24, 2008 at 9:39 pm

Let me see a novel idea... How about you stop having anal sex.

I will accept my nobel prize for medicine now.

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Posted by SUMD
a resident of Stanford
on Mar 25, 2008 at 1:08 pm

We need to prosecute HIV+ gay males who continue to have sex with others.

Of course we should also prosecute HIV+ heterosexuals who risk spreading this disease.

There is no cure for HIV/AIDS current treatments can keep people alive longer but the price is very high in $ and human suffering.

These patients experience accelerated aging so that at age 50 they have the medical conditions typically seen in 80 tr olds

In addition these patients take massive amounts of antibiotics which is causing resistant strains of life threatening infections like MRSA

SAN FRANCISCO, Jan. 14 - Methicillin-resistant Staphylococcus aureus (MRSA) may have become a sexually transmitted disease among gay men, researchers here said.

Gay men are 13 times more likely to be infected with a multi-drug-resistant strain of MRSA than are other members of the community, according to Bihn An Diep, Ph.D., of the University of California San Francisco, and colleagues.