Stanford grad Nicole Gibbs and her doubles partner Alison Riske dropped a 7-5, 6-4 decision to Klaudia Jans-Ignacik and Karolina Plishkova on Monday in the first round of action at the Western and Southern Open in Cincinnati.
Gibbs and Riske could not take advantage of nine double faults, nor could they match five aces.
The former two-time NCAA singles champion returns to the court Tuesday to face Christina McHale in a first round match. It will mark Gibbs' main draw debut in her hometown tournament.
Ninth-seeded and former world No. 1 Ana Ivanovic awaits the winner.
Gibbs, who is ranked a career-high 141, will be playing in her first main draw since reaching the finals in Lexington, where she lost to Madison Brengle.
By reaching the finals, Gibbs nailed down a wild card into the U.S. Open. She'll be making her third appearance in the main draw at the final Grand Slam event of the season.
Gibbs beat veteran Francesca Schiavone in three sets just to qualify for the main draw. She meets another tough rival in McHale, who has a 2-0 all-time record against Gibbs.