Posted by Jared Bernstein, a resident of the Professorville neighborhood, on Dec 5, 2011 at 11:44 am
Can this have a cover or other FEATURED coverage in the printed Weekly?
The last time I saw an article about such a thing (a Palo Alto kid won an international math competition), it was covered on-line, but merited only a one-sentence blurb in the print version. So, I never found out more about the kid involved or saw a picture of him.
So, can we give them at least as much coverage as the Sacred Heart cross-country runners and the like?
I am generally interested in understanding the structure, mechanism of action, and enzymology (inhibition) of proteins that lead to infectious disease, inflammation, and cancer. My research projects are multidisciplinary and include structural biology, enzymology, structural genomics, bioinformatics, mutational analysis, high throughput screening, inhibitor design, and structure-activity relationship investigation. Exploring the mechanism of enzyme catalysis to answer those fundamental questions in our textbook is another field of my research. In particular of interest, I have worked on the mechanisms involved in carbon bond cleavage and formation going through Schiff base intermediate, which may provides some novel strategies in protein conjugation for drug development.