The mandate — which follows the death of 10 California infants in a whooping-cough epidemic last year — comes from a new law signed last September by former Gov. Arnold Schwarzenegger.
The Palo Alto Medical Foundation (PAMF) has "no shortage" of the vaccination, a spokeswoman said.
"The new state regulation is that all students between seventh and 12th grade need (the pertussis booster) because the childhood vaccination doesn't give lifelong immunity," PAMF Public Affairs Manager Cynthia Greaves said.
For the 2011-12 school year, all students entering any grade from 7 to 12 will need proof of the booster, known as Tdap.
For 2012-13 and future school years, all students entering seventh grade — or those newly registering for seventh through 12th grade in a California district or private school — will need proof of the Tdap shot.
Palo Alto Unified School District Nurse Linda Lenoir said she was talking with medical foundation representatives to try to smooth access to the booster shot for the approximately 5,700 Palo Alto students in seventh through 12th grades.
The California Department of Public Health urged parents not to wait for the new school year to get children vaccinated since "there will be no grace period, and the regulations will be strictly enforced."
More information is posted at shotsforschool.org, sponsored by the California Public Health Department.
In calendar 2010, 8,383 cases of whooping cough, including 10 infant deaths, were reported throughout California, according to a preliminary count by the federal Centers for Disease Control and Prevention (CDC).
It was the highest number of reported cases since 1947, when 9,934 cases were reported, and the highest incidence of cases since 1958, when there were 26 cases per 100,000 population, the CDC said.