"I have been truly blessed to have worked at Stanford for the past 11 seasons," said Simon. "Stanford University is the best environment in the world to develop young people to their fullest potential.
"It has been a privilege for me and my family to be a part of this great educational endeavor. I appreciate the opportunity to work with so many exceptional student-athletes, talented coaches, and dedicated administrators and staff."
Stanford just completed the 2011 season with a 3-0 win over California last Friday in Berkeley. The win completed a 6-10-2 campaign that included a tie for fourth finish in the Pac-12.
Simon's best seasons came in 2001 and 2002, his first two at Stanford. Those teams went a combined 36-7-4 and both played in the College Cup. The 2002 team made the final, losing 1-0 to UCLA.
The other trip to the NCAA tournament came on 2009, when the Cardinal finished 12-6-2 led by future MLS first-round pick Bobby Warshaw. Stanford won two games in the tournament before eventually losing to top-seeded Akron in the Round of 16.
A nationwide search for Simon's replacement will begin immediately.