Melvin, 49, will join the team in Chicago, where the A's are begin a four-game series with the White Sox. He will finish the 2011 season on an interim basis. The A's are currently 27-36 and in last place in the American League West following a 3-2 loss to Baltimore on Wednesday night.
This will be Melvin's third stint as manager. He began his career with Seattle in 2003. He took over the Arizona Diamondbacks in 2005 and became the team's 'all-time winningest manager. Melvin has compiled an overall record of 493-508 in seven seasons as a Major League manager from 2003-09.
In his rookie managerial season, he directed the Mariners to a 93-69 record in 2003. Four years later, he won National League Manager of the Year honors after guiding Arizona to a league-best 90-72 mark and the NL West Division title in 2007.
Melvin also served as the Diamondbacks' bench coach on Bob Brenly's coaching staff from 2001-02, when Arizona won the World Series in 2001 and the NL West Division championship in 2002.
Melvin graduated from Menlo-Atherton in 1979 and later attended and played baseball at the University of California. The Detroit Tigers selected him as its first choice in the secondary phase of the 1981 January draft.
The former catcher posted a .233 batting average with 35 home runs and 212 RBI while playing in 692 games during his 10-year Major League career with the Tigers (1985), San Francisco Giants (1986-88), Baltimore Orioles (1989-91), Kansas City Royals (1992), Boston Red Sox (1993), New York Yankees (1994) and Chicago White Sox (1994).